Urolithin A (1143-70-0) phofo - Mofani oa thepa ea moetsi
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Urolithin A.

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Urolithin A ke metabolite ea bobeli ea ellagic acid, polyphenolic antioxidant, e nang le lithibela-mafu, anti-inflammatory le anti-oxidant.
E tsebahala: Urolithin A 8-Methyl Ether (CAS: 35233-17-1) e mahareng ha ho qaptjoa Urolithin A, e leng metabolite e kholo ea Ellagitannin hape e bonts'a thepa e khahlanong le ho ruruha le antioxidant.

Tlhaloso ea Sehlahisoa

Litšobotsi tsa Motheo

Name Product Urolithin A.
Nomoro ea CAS 1143-70-0
Molecular Formula C13H8O4
Boima ba 'mele 228.2
Li-synonyms 2 ', 7-Dihydroxy-3,4-benzocoumarin

3,8-Dihydroxy Urolithin;

Urolithin A 8-Methyl Ether;

3-Hydroxy-8-methoxy-6H-dibenzo [b, d] pyran-6-e le 'ngoe.

Ponahalo Phosente e tšoeu ea kristale
Ho Boloka le ho Sebetsana E omme, e lefifi ebile e le 0 - 4 C ka nako e khuts'oane (matsatsi ho isa ho libeke) kapa -20 C nako e telele (likhoeli ho isa ho lilemo).

 

Reference

[1] Mofani, S. et al. DNA ea Mitochondrial e hlakola liseleng tsa satellite tsa mesifa: se boleloang ke kalafo Hum. Mol. Liphatsa tsa lefutso. La 22, 4739-4747 (2013)

[2] Bialonska D, Kasimsetty SG, Khan SI, Ferreira D (11 Pulungoana 2009). "Li-Urolithin, methapo ea methapo ea mala ea likharenate ellagitannins, e bonts'a tšebetso e matla ea antioxidant ka tlhahlobo ea sele" J Agric Lijo Chem. 57 (21): 10181-6. doi: 10.1021 / jf9025794. PMID 19824638.

[3] Milburn, MV & Lawton, KA Ts'ebeliso ea metabolism ho hlahloba ts'oaetso ea insulin. Annu. Moruti Med. 64, 291-305 (2013).

[4] Cerdá, Begoña; Tomás-Barberán, Francisco A .; Espín, Juan Carlos (2005). "Metabolism ea Antioxidant le Chemopreventive Ellagitannins e tsoang ho Fragole, Raspberries, Walnuts, le Veine e Tsofetseng ea Batho ho Batho: Boitsebiso ba Li-Biomarkers le Phapang ea Motho ka Mong". Tlaleho ea Chemistry ea Temo le Lijo. 53 (2): 227-235. doi: 10.1021 / jf049144d. PMID 15656654.

[5] Laker, RC le al. Phosphorylation ea Ampk ea Ulk1 ea hlokahala bakeng sa ho lebisa mitochondria ho lysosomes ho mitophagy e bakoang ke boikoetliso. Nat. Komello. 8, 548 (2017).