Reka Abiraterone (154229-19-3) hplc≥98% | Barekisi ba AASraw
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Abiraterone (154229-19-3)

Rating: SKU: 154229-19-3. Category:

AASraw e na le tšebeliso le bokhoni ba tlhahiso ho tloha gram ho isa ho boima ba Abiraterone (154229-19-3), tlasa taolo ea CGMP le tsamaiso ea tsamaiso ea boleng.

Tlhaloso ea Sehlahisoa

 

Abiraterone (154229-19-3) tsa video

 

 


 

Abiraterone (154229-19-3) Specification:

Khemikhale ea Lik'hemik'hale: Name Product: Abiraterone
Reka Abiraterone (154229-19-3) hplc≥98% | Barekisi ba AASraw Cas.: 154229-19-3
Molecular Formula: C24H31NO
Boima ba 'mele: 349.5
Li-synonyms: Abiraterone

154229-19-3

17- (3-Pyridyl) androsta-5,16-dien-3beta-ol

CB 7598

CB-7598

Sesebelisoa: E omileng, e lefifi
Litokomane (COA & HPLC jj.): fumaneha

 

Abiraterone (154229-19-3) Dtlhahlobo:

Abiraterone phofo, eo hape e tsejoang e le CB7598, ke metabolism e sebetsang ea abiraterone acetate, e leng ester ester e sebetsang ka molomo ea steroidal komponeng abiraterone e nang le ts'ebetso ea antiandrogen, e sebelisetsoang ho phekola mofets'e oa metastatic, cast-resistant prostate cancer.

E sebelisoa e le O-acetate, e sebelisetsoa kalafo ea mofets'e oa methapo ea methapo ea methapo. E na le karolo e le moemeli oa antineoplastic le inhibitor ea EC 1.14.99.9 (steroid 17alpha-monoo oxygenase) inhibitor. Ke 3beta-sterol le setho sa li-pyridine. E tsoa hydride ea androstane.

 

Tlhaloso:

  • 1: Grist E, Attard G. Nts'etsopele ea abiraterone acetate bakeng sa kankere ea methapo ea methapo. Urol Oncol. 2015 Jun; 33 (6): 289-294. Doi: 10.1016 / j.urolonc.2015.03.021. Tlhahlobo. PubMed PMID: 26025264.
  • 2: Petrelli F, Coinu A, Borgonovo K, Cabiddu M, Ghilardi M, Lonati V, Barni S. Enzalutamide Kamora kalafo ea Docetaxel le Abiraterone Acetate ho Prostate Cancer: Tlhahlobo ea Pooled ea Li-Case tse 10. Kankere ea Clin Genitourin. 2015 Jun; 13 (3): 193-198. Doi: 10.1016 / j.clgc.2014.10.006. Epub 2014 Nov 7. Tlhahlobo. PubMed PMID: 25466676.
  • 3: Giacinti S, Bassanelli M, Aschelter AM, Milano A, Roberto M, Marchetti P. Resistance ho abiraterone mofetsong oa kankere ea senya ea maqhubu: tlhahlobo ea lingoliloeng. Resicancer Res. 2014 Nov; 34 (11): 6265-9. Tlhahlobo. PubMed PMID: 25368223.
  • 4: Zobniw CM, Causebrook A, Fong MK. Tšebeliso ea Clinical ea abiratone kalafong ea mofets'e oa methapo ea methapo ea methapo. Res Rep Urol. 2014 Aug 5; 6: 97-105. Doi: 10.2147 / RRU.S29003. eCollection 2014. Tlhahlobo. PubMed PMID: 25157341; PubMed Central PMCID: PMC4128838.
  • 5: Francini E, Petrioli R, Roviello G. Ha ho na bopaki bo hlakileng ba melemo ea bongaka ea mofuta o latelang oa kalafo ea kalafo o nang le abiraterone acetate le enzalutamide. Setsebi Rev Anticancer Ther. 2014 Oct; 14 (10): 1135-40. Doi: 10.1586 / 14737140.2014.949677. Epub 2014 Aug 19. Tlhahlobo. PubMed PMID: 25135334.