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Nicotinamide riboside chloride

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Tlhaloso ea Sehlahisoa

Litšobotsi tsa Motheo

Name Product Nicotinamide riboside chloride
Nomoro ea CAS 23111-00-4
Molecular Formula C11H15ClN2O5
Boima ba 'mele 290.7
Li-synonyms 23111-00-4

Nicotinamide riboside chloride

Nicotinamide riboside (chloride)

3-Carbamoyl-1-((2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride

Nicotinamide ribose chloride

Ponahalo Pula e tšoeu
Ho Boloka le ho Sebetsana 0 - 4 C bakeng sa nako e khuts'oane (matsatsi ho isa ho libeke), kapa -20 C nako e telele (likhoeli).

 

Tlhaloso ea Nicotinamide riboside chloride

Nicotinamide Riboside Chloride (NIAGEN) ke mofuta o nang le letsoai le nang le letsoai la nicotinamide riboside (NR) .NR ke mofuta o mocha oa pyridine-nucleoside oa vithamine B3 e sebetsang e le selelekela sa nicotinamide adenine dinucleotide (NAD) kapa NAD +. (GRAS) naheng ea United States bakeng sa tšebeliso ea lihlahisoa tsa lijo. Nicotinamide riboside chloride ke mofuta oa kristale oa Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride e eketsa maemo a NAD [+] 'me e kenya tšebetsong SIRT1 le SIRT3, e fihlang sehlohlolong ka metabolism e matlafatsang le ts'ireletso khahlano le ho sa tloaelehang hoa metabolism. Nicotinamide riboside chloride phofo e sebelisoa lijong tse tlatsetsang.

 

Mokhoa oa Ketso oa Nicotinamide riboside chloride

Nicotinamide Riboside Chloride (NIAGEN) ke mofuta oa letsoai la chloride oa nicotinamide riboside (NR). NR ke mofuta oa pyridine-nucleoside oa vithamine B3 e sebetsang e le selelekela sa nicotinamide adenine dinucleotide kapa NAD +. NR e thibela ho senyeha ha methapo ea methapo ea mokokotlo ea methapo ea kutlo le ho sireletsa khahlanong le tahlehelo ea kutlo e bakoang ke lerata ho litoeba tse phelang. Nicotinamide riboside phofo e thibela mesifa, methapo ea methapo le melanocyte stem cell senescence. Ho nchafatsoa ha mesifa ho litoeba ho bonoe kamora kalafo ka nicotinamide riboside, e lebisang khopolong ea hore e ka ntlafatsa ntlafatso ea litho tse kang sebete, liphio le pelo. Nicotinamide riboside e boetse e theola tsoekere ea mali le sebete se mafura ka li-prediabetic le mofuta oa 2 oa mefuta ea lefu la tsoekere ha e ntse e thibela nts'etsopele ea lefu la tsoekere la pheripheral neuropathy. Tlhokomeliso: Nicotinamide Riboside chloride ke motsoako oa α / β.

 

Kopo ea Nicotinamide riboside chloride

Nicotinamide riboside chloride phofo e ngolisitsoe ka nomoro ea CAS 23111‐00‐4 le EC nomoro ea 807‐820. Lebitso la lona la IUPAC ke 5 - [(1R, 2R, 3S, 4R) ,5 ‐ dihydroxy ‐ 3,4‐ (hydroxymethyl) oxolan ‐ 5 ‐ yl] pyridin ‐ 2 ‐ ium ‐ 1 ‐ carboxamide; chloride. Tsela ea molek'hule ea nicotinamide riboside chloride ke C3H11N15O2Cl, le boima ba eona ba limolek'hule 5 g / mol. Nicotinamide Riboside Chloride (NIAGEN) ke mofuta oa letsoai la chloride oa nicotinamide riboside (NR) .NR ke mofuta o mocha oa pyridine-nucleoside oa vithamine B290.7 e sebetsang e le selelekela sa nicotinamide adenine dinucleotide (NAD) kapa NAD +. 'Mele o hloka NAD + ho sebetsa ka mokhoa o tloaelehileng. Maemo a tlase a NAD + a ka baka mathata a bongaka. Ho nka nicotinamide riboside ho ka thusa ho nyolla maemo ana a tlase a NAD +.

 

Melemo ea ho Nicotinamide riboside chloride

Nicotinamide riboside Chloride, selelekela sa NAD + se sebetsang ka molomo, e eketsa maemo a NAD + mme e kenya tšebetsong SIRT1 le SIRT3. Nicotinamide riboside Chloride phofo ke mohloli oa vithamine B3 (niacin) mme ts'ebeliso ea phofo ea Nicotinamide riboside Chloride e ka ntlafatsa metabolism ea oxidative, ts'ireletso khahlano le ho sa tloaelehang hoa metabolism. Nicotinamide riboside Chloride e fokotsa ho senyeha ha mohopolo ka har'a mofuta oa toeba oa lefu la Alzheimer's.

 

Reference

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