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Trastuzumab (180288-69-1)

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AASraw e na le bokhoni ba tlhahiso le tlhahiso ho tloha ho gram ho ea ka taelo ea Trastuzumab (CAS 180288-69-1), tlas'a taolo ea CGMP le tsamaiso ea mokhoa oa ho laola boleng.

Trastuzumab powder e sebelisoa ho phekola kankere ea matsoele ea HER2-positive. HLXMUMX e feteletseng ea protheine e fumanoa ka 2% -25% ea kankere ea matsoele e ka sehloohong.Trastuzumab e bontsitsoe, ka bobeli litlhapi tsa li-vitro le liphoofolong, ho thibela ho ata ha likokoana-hloko tsa batho tse hlahisang HER30.

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Trastuzumab tsa basebetsi ba bohlokoa

Name: Trastuzumab
CAS: 180288-69-1
Molecular Formula: C10H14N6O5
Boima ba 'mele: 298.25536
Melt Point: 61-71 ° C
Temp Temp Storage: 2-8 ° C
Color: Pula e tšoeu


Trastuzumab (180288-69-1) tshebeliso ea potoloho ea steroids

Mabitso

Trastuzumab (CAS 180288-69-1), lebitso la khoebo ke Herceptin.

Sebeliso ea Trastuzumab

Trastuzumab e fanoa ka ho kenngoa ha motsoako ho kenngoa liphate (intravenous, IV). Lethal dose ea pele e fuoa metsotso ea 90. Haeba litebelisuoa tse latelang tsa tlhokomelo li ka fanoa ka makhetlo a 30.
Chelete ea Trastuzumab (180288-69-1) eo u tla e fumana e itšetlehile ka lintlha tse ngata, tse kenyeletsang bophahamo ba hao le boima ba hao, bophelo bo botle ba hau kapa mathata a mang a bophelo bo botle, le mofuta oa kankere kapa boemo bo tšoaroang. Ngaka ea hau e tla etsa qeto ea tekanyo ea hao le kemiso ea hau.

Temoso ho Trastuzumab

Tšusumetso e mpe e sa tloaelehang empa e sa tloaeleha ea Trastuzumab e ka kena-kenana le khato ea ho phunya pelo. Ho ba le mathata a pelo (ho hloleha ha pelo) ho eketseha ho batho ba nang le lefu la pelo kapa lintho tse ling tse kotsi, tse kang mahlaseli a sefubeng, botsofali, le tšebeliso ea lithethefatsi tse ling tsa pelo (tse kang doxorubicin le cyclophosphamide). Ngaka ea hau e ka hlahloba pelo ea hau pele u ka nka Trastuzumab leha e le efe 'me e tla hlahloba pelo ea hao haufi-ufi nakong ea phekolo ea hau. Trastuzumab (180288-69-1) e ka emisoa haeba matšoao a pelo a hlōleha.

Litaelo tse ling

Li-antibodies tsa monoclonal ke mofuta o mocha oa phekolo ea kankere e "lebisitsoeng". Li-antibodies ke karolo ea sesole sa 'mele. Ka tloaelo, 'mele o etsa li-antibodies ho arabela ka antigen (e kang protheine e nyenyane) e kenang' meleng. Li-antibodies li ikopanya le antigen e le hore li e tšoaee ka timetso ea 'mele ea' mele. Le laborateng, bo-rasaense ba hlahloba likokoana-hloko tse khethehileng holim'a lisele tsa kankere (sepheo) ho fumana hore na protheine e tšoana le antigen. Joale, ho sebelisa liphoofolo le liprotheine tsa batho, bo-rasaense ba sebetsa ho theha setho se khethehileng sa anti-antibody se tla ikamahanya le sepheo sa antigen. Li-antibodies li tla ikamahanya le li-antigens tse tšoanang le senotlolo se lumellanang le senki. Theknoloji ena e lumella kalafo ho lebisa lisele tse khethehileng, e leng se bakang chefo e nyenyane liseleng tse phetseng hantle. Monoplonal antibody therapy e ka etsoa feela bakeng sa kankere eo likokoana-hloko (le li-antibodies) li khethiloeng.

Trastuzumab e sebetsa ka ho lebisa tlhokomelo ho mokhatlo oa HER2 / neu ka lisele tsa kankere. Genesa ea HER2 e hlahisa pulo ea protheine ka seleng e holim'a lisele tse bontšang kgolo e tloaelehileng ea sele ka ho bolella sele hore e arohane le ho ata. Tse ling tsa mafura a kankere a nang le kankere li na le HER2 haholo (HER2 / neu overexpression), e etsang hore lisele li arohane le ho ata ka potlako haholo. Trastuzumab (180288-69-1) e ikopanya ho li-receptor tsa HER2 ho thibela lisele hore li se ke tsa ata, ho thibela ho eketseha ha kankere le ho liehisa tsoelo-pele ea kankere. E ka boela ea sebetsa ka ho susumetsa mokhoa oa ho itšireletsa mafung.


Joang ho reka Trastuzumab ho tloha AASraw

1.To iteanye le rona ka imeile ea rona lenaneo la lipatlisiso, kapa skype ea inthanetengmoemeli oa tšebeletso ea bareki (CSR).
2.To re fane ka lipotso tsa hau le lipotso tsa hau.
3.Our CSR e tla u fa tlhaloso, nako ea ho lefa, nomoro ea ho latela, litsela tsa ho pepa le letsatsi la ho fihla ho fihlela (ETA).
4.Payment e entsoe mme thepa e tla romelloa ka lihora tsa 12 (Ho laela ka hare ho 10kg).
5.Goods e amohetse mme e fana ka litlhaloso.

TLHOKOMELISO LE TLHALOSO:

Boitsebiso bona bo rekisetsoe tšebeliso ea lipatlisiso. Lipehelo tsa thekiso Etsa kopo. Eseng molemong oa tšebeliso ea batho, kapa bongaka, bongaka ba liphoofolo kapa lisebelisoa tsa lapeng.


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