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Pyridoxal-5-phosphate monohydrate

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SKU: 41468-25-1. Category:

AASraw e na le bokhoni ba tlhahiso ea tlhahiso le tlhahiso ho tloha ho gram ho isa boemong bo bongata ba Pyridoxal-5-phosphate Monohydrate (41468-25-1), tlas'a taolo ea CGMP le tsamaiso ea mokhoa oa ho laola boleng.

Pyridoxal-5-phosphate phofo ea Monohydrate, Vithamine B6 metabolite e sebetsang joaloka coenzyme ho etsa liphetoho tsa transamination ka ho etsa li-schiff-base le lihlopha tsa li-lysine ho aminotransferase. E boetse e sebetsa e le coenzyme ho latela li-decarboxylation le liketso tsa ho silafatsa likokoana-hloko. E ka fetola lisebelisoa tsa lysyl le li-valyl liprotheine. O na le bokhoni ba ho thibela li-receptor tsa purinergic le tšusumetso ea intracellular ea Ca2 +.

Tlhaloso ea Sehlahisoa

Pyridoxal-5-phosphate video ea monohydrate


Pyridoxal-5-phosphate Monohydrate ea bohlokoa

Name: Pyridoxal-5-phosphate monohydrate
CAS: 41468-25-1
Molecular Formula: C8H12NO7P
Boima ba 'mele: 265.16
Melt Point: 2-8 ° C
Temp Temp Storage: Mocheso oa kamore
Color: Pale Yellow Crystalline


Pyridoxal-5-phosphate potoloho ea Monohydrates

1. Mabitso:
Mabitso a Lik'hemik'hale: Pyridoxal- 5'-phosphate monohydrate, 3-Hydroxy-2-methyl-5 - ([phosphonooxy] methyl) -4-pyridinecarboxaldehyde
Codecarboxylase
Mabitso a mang: Vithamine B6, Pyridoxal Phosphate, PLP

Pyridoxal-5-phosphate Monohydrate Usage

Vithamine B6 metabolite e sebetsang joaloka coenzyme ka liphetoho tsa transamination ka ho etsa setsi sa basebetsi ba Schiff le lihlopha tsa lysine holim'a li-aminotransferase. E boetse e sebetsa e le coenzyme ho latela li-decarboxylation le liketso tsa ho silafatsa likokoana-hloko. E ka fetola lisebelisoa tsa lysyl le li-valyl liprotheine. O na le bokhoni ba ho thibela li-receptor tsa purinergic le tšusumetso ea intracellular ea Ca2 +.

Ke tekanyo efe ea Pyridoxal-5-phosphate monohydrate

PLP e na le thuso bakeng sa ho fetola litlhaka tsa lysyl le valyl le ho sebetsa e le coenzyme ho etsa liphetoho tsa transamination ka ho etsa setsi sa basebetsi ba Schiff le lihlopha tsa lysine ho aminotransferase
PLP ke mofuta o sebetsang oa vithamine B6
E boetse e sebetsa e le coenzyme ho latela li-decarboxylation le liketso tsa ho silafatsa likokoana-hloko

Kamoo monohydrate ea Pyridoxal-5-phosphate e sebetsang kateng

Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), mofuta o sebetsang oa vithamine B6, ke coenzyme ka mekhoa e fapa-fapaneng ea lik'hemik'hale. Komiti ea Enzyme e thathamisitse mesebetsi e mengata e itšetlehileng ka 140 PLP, e lumellanang le ~ 4% ea mesebetsi eohle e hlalositsoeng. Mekhoa e metle ea PLP e hlahisoa ke bokhoni ba eona ba ho tlama ka tlas'a eona substrate, ebe e sebetsa joaloka motsoako oa electrophilic, kahoo ho tsitsisa mefuta e fapaneng ea likarabo tsa carbanionic.

PLP e sebetsa e le coenzyme liketsong tsohle tsa transamination, 'me ka mokhoa o itseng oa ho hlahisa lik'hemik'hale, ho silafatsoa, ​​le ho itšoara ka tsela ea racemization ea amino acid. Sehlopha sa aldhyde se entsoeng ka li-schiff (basebelisi ba ka hare) le sehlopha sa ε-amino sa sehlopha se itseng sa lysine sa enzyme ea aminotransferase. Sehlopha sa α-amino sa substrate sa amino acid se senya sehlopha sa ε-amino sa libaka tsa maiketsetso tsa lysine sebakeng se tsejoang e le transaldimination. Sephetho se ka ntle se ka hlahisa proton, carbon dioxide, kapa amino acid e se e le moeeng oa quinoid, eo ka nako e tšoanang e ka bang nucleophile litseleng tse 'maloa tsa litsela.

Ha ho e-na le pheko ea pheko ea metsi, ka mor'a hore motho a senyehe, motsoako oa quinoid o amohela proton sebakeng se fapaneng hore e be ketimine. Ketimine e hlahisoang ke hydrolysed e le hore sehlopha sa amino se lule se rarahaneng. Ho phaella moo, PLP e sebelisoa ke aminotransferase (kapa transaminase) e sebetsang ka tsoekere e sa tloaelehang e kang perosamine le desosamine. Liketsong tsena, PLP e arabela le glutamate, e fetisang sehlopha sa eona sa alpha-amino ho PLP ho etsa pyridoxamine phosphate (PMP). PMP e ntan'o fetisetsa naetrojene ea eona ho tsoekere, ho etsa tsoekere ea amino.

PLP e boetse e ameha ka mekhoa e sa tšoaneng ea ho felisa beta e kang liketso tse entsoeng ke serine dehydratase le GDP-4-keto-6-deoxymannose-3-dehydratase (ColD).

E boetse e sebetsa ka mokhoa oa condensation ho heme synthesis. PLP e phetha karolo ea phetoho ea levodopa ho dopamine, e thusa ho fetoha ha glutamate ea methapo ea kutlo ea pelo ho GABA, e leng ho lumella SAM hore e be decarboxylated ho theha propylamine, e leng pele ho polyamine.

temoso ea

Ena ke mofuta o sebetsang oa VITAMIN B 6 e sebetsang e le coenzyme bakeng sa tlhahlobo ea amino acid, li-neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Nakong ea phetolo ea li-amino acid, pyridoxal phosphate e fetoloa ho fetoha pyridoxamine phosphate (PYRIDOXAMINE).
ho tloha ho MeSH
Pyridoxal Phosphate ke mofuta o sebetsang oa vithamine B6 le coenzyme bakeng sa li-enzyme tse ngata tse itšetlehileng ka pyridoxal phosphate (PLP). PLP e kenyelelitsoe mekhoeng e mengata ea phekolo ea li-enzymatic, decarboxylation le liketso tsa ho silafatsa likokoana-hloko; ho hlokahala bakeng sa ho qaptjoa ha amino acid le amino acid metabolites, le bakeng sa ho qaptjoa le / kapa ts'oaetso ea li-neurotransmitters tse itseng, ho kenyelletsa le ho fetoha ha glutamate ho gamma-aminobutyric acid (GABA) le levodopa ho dopamine. PLP e ka sebelisoa e le ho tlatsetsa ha lijo meleng ea vithamine B6. Maemo a fokotsehileng a PLP bokong a ka baka ho se sebetse ha methapo ea pelo.
Pharmacology ho tloha NCIt
Ena ke mofuta o sebetsang oa vithamine B6 e sebetsang e le coenzyme bakeng sa tlhahlobo ea amino acid, li-neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Nakong ea phetolo ea li-amino acid, pyridoxal phosphate e fetoloa ka nako e khutšoanyane e le pyridoxamine phosphate (pyridoxamine). - Pubchem; Pyridoxal-phosphate (PLP, pyridoxal-5'-phosphate) ke motsoako oa liphetoho tse ngata tsa enzymatic. Ke mofuta o sebetsang oa vithamine B6 e nang le metsoako e meraro ea tlhaho, pyridoxal, pyridoxamine le pyridoxine.

Pyridoxal-5-phosphate Monohydrate Raw Recipes

Ho botsa bareki ba rona baemeli ba rona (CSR) bakeng sa lintlha tse eketsehileng, bakeng sa boitsebiso ba hau.

Pyridoxal-5-phosphate Khoebo ea Monohydrate

Ho fanoa nakong e tlang.

Na pyridoxal-5-phosphate monohydrate e na le liphello tse mpe

Pyridoxal Phosphate ke mofuta o sebetsang oa vithamine B6 le coenzyme bakeng sa li-enzyme tse ngata tse itšetlehileng ka pyridoxal phosphate (PLP). PLP e kenyelelitsoe mekhoeng e mengata ea phekolo ea li-enzymatic, decarboxylation le liketso tsa ho silafatsa likokoana-hloko; ho hlokahala bakeng sa ho qaptjoa ha amino acid le amino acid metabolites, le bakeng sa ho qaptjoa le / kapa ts'oaetso ea li-neurotransmitters tse itseng, ho kenyelletsa le ho fetoha ha glutamate ho gamma-aminobutyric acid (GABA) le levodopa ho dopamine. PLP e ka sebelisoa e le ho tlatsetsa ha lijo meleng ea vithamine B6. Maemo a fokotsehileng a PLP bokong a ka baka ho se sebetse ha methapo ea pelo.


Ho reka Pyridoxal-5-phosphate monohydrate ho tloha AASraw

1.To iteanye le rona ka imeile ea rona lenaneo la lipatlisiso, kapa skype ea inthanetengmoemeli oa tšebeletso ea bareki (CSR).
2.To re fane ka lipotso tsa hau le lipotso tsa hau.
3.Our CSR e tla u fa tlhaloso, nako ea ho lefa, nomoro ea ho latela, litsela tsa ho pepa le letsatsi la ho fihla ho fihlela (ETA).
4.Payment e entsoe mme thepa e tla romelloa ka lihora tsa 12 (Ho laela ka hare ho 10kg).
5.Goods e amohetse mme e fana ka litlhaloso.

TLHOKOMELISO LE TLHALOSO:

Boitsebiso bona bo rekisetsoe tšebeliso ea lipatlisiso. Lipehelo tsa thekiso Etsa kopo. Eseng molemong oa tšebeliso ea batho, kapa bongaka, bongaka ba liphoofolo kapa lisebelisoa tsa lapeng.


COA

HNMR

Recipes

Pyridoxal-5-phosphate e Monohydrate Raw Recipes

Ntho e nyenyane 10grams.
Tlhahlobo ka bongata bo tloaelehileng (ka hare ho 1kg) e ka romeloa lihora tse 12 kamora ho lefa.
Bakeng sa taolo e kholo e ka romeloa matsatsing a ts'ebetso ea 3 ka mor'a ts'enyehelo.

Litlhaloso le lihlahisoa tsa lihlahisoa