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Nuciferine phofo

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SKU: 475-83-2. Category:

AASraw e na le bokhoni ba tlhahiso le tlhahiso ho tloha ho gram ho ea ka taelo e kholo ea phofo ea Nuciferine (475-83-2), tlas'a taolo ea CGMP le tsamaiso ea tšebetso ea boleng bo sebetsang.

Nuciferine phofo ke alkaloid e fumanehang ka har'a limela Nymphaea caerulea le Nelumbo nucifera. E na le boikutlo ba liketso bo amanang le dopamine receptor blockade.Ka etsa hore sedation, hypothermia, ptosis, le (ka tekanyo e phahameng) e be le catalepsy; e thibela tšebetso ea motlakase ka nako e le 'ngoe, phekolo ea ho qoba, amphetamine chefo le maqiti. Nuciferine phofo e ka boela ea e-ba le tšusumetso ea morphine analgesia. Lethal dose e bolaeang ka har'a litoeba ke 289 mg / kg. E na le kamano e amanang le apomorphine.

Tlhaloso ea Sehlahisoa

Nuciferine phofo ea video


Lihlahisoa tse tala tsa Nuciferine tsa basebetsi ba bohlokoa

Name: Nuciferine phofo
CAS: 475-83-2
Molecular Formula: C19H21NO2
Boima ba 'mele: 295.38
Melt Point:
Temp Temp Storage: Sehatsetsi
Color: Tšoeu kapa u tlohele phofo e tšoeu ea Crystalline


Nko e tala ea Nuciferine e senyeheloang ke boima ba 'mele

Mabitso

(6aR)-1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline, Nuciferine powder (CAS 475-83-2)

Tšebeliso ea phofo ea Raw Nuciferine

Nuciferine phofo ke alkaloid e fumanehang ka har'a limela Nymphaea caerulea le Nelumbo nucifera. E na le boikutlo ba liketso bo amanang le dopamine receptor blockade.Ka etsa hore sedation, hypothermia, ptosis, le (ka tekanyo e phahameng) e be le catalepsy; e thibela tšebetso ea motlakase ka nako e le 'ngoe, phekolo ea ho qoba, amphetamine chefo le maemo a tsitsitseng. Nuciferine phofo e ka boela ea e-ba le tšusumetso ea morphine analgesia. Lethal dose e bolaeang ka har'a litoeba ke 289 mg / kg. E na le kamano e amanang le apomorphine.

1.Nuciferine phofo e tala ke ntho e kholo ea aporphine alkaloid e tsoang makhasi a N. nucifera Gaertn ea nang le anti-hyperlipidemia, mesebetsi ea anti-hypotensive, anti-arrhyth, le insulin secretagogue.
2. Nuciferine phofo ke motsoako oa bohlokoa oa lithethefatsi bakeng sa ho phekola maloetse a amanang le botenya, ka ho matlafatsoa ke lefu la ho fokotsa lefu la HFD le lefu la sebete le kotsi.
3. Nuciferine phofo e tala e ka 'na ea e-ba monyetla oa ho thibela le ho phekola lefu la hyperuricemia le ho ruruha ha liphio.
4. Nuciferine phofo e na le phello e sa tloaelehang ka mekhoa e mabeli ea endothelium le-e sa sebeliseng, e fana ka maikutlo a hore phofo ea Nuciferine e ka ba le phekolo ea mafu mafu a mangata a amahanngoa le ho hlaseloa ha mesifa.
5. Nuciferine phofo e tala, e nkiloeng ho Nelumbo nucifera, e ka susumelletsa likarolo tse peli tsa insulin ho boloka likhutsana ka likhutsana tse ka thōko ka ho koala litsela tsa potassium-adenosine triphosphate, ho hlalosa liphello tse khahlanong le lefu la tsoekere la Nelumbo nucifera.
6. Nuciferine phofo (CAS 475-83-2) e thibela phello e hlahisang bohloko ea nikotine e amanang le Wnt / ß-catenin e bontšang kankere e seng e nyane ea kankere ea matšoafo, e fana ka mekhoa e meng e ka sebelisoang ho thibelo ea phekolo ea HIV le NSCLC.

Temoso ea phofo ea Raw Nuciferine

Ho fana ka polokelo ho boleloa ka sehlahisoa se hlahisoang ke sehlahisoa 'me sekoahelo se bolokiloe ka thata, sehlahisoa se ka bolokoa ho fihlela likhoeling tsa 24 (2-8C).
Kae kapa kae moo ho ka khonehang, o lokela ho itokisetsa le ho sebelisa tharollo ka letsatsi le le leng. Leha ho le joalo, haeba u hloka ho iketsetsa tharollo ea thepa esale pele, re khothaletsa hore u boloke tharollo e le li-aliquots lipaleng tse tiisitsoeng ka thata -20C. Ka kakaretso, tsena li tla sebelisoa ho fihlela libeke tse peli. Pele o sebedisa, mme pele o bula sehlabelo re kgothaletsa hore o dumelle sehlahisoa sa hau hore se lekanyetse mocheso oa kamore bonyane hora ea 1.

Ho kenngoa ha sehlahisoa seo se ka 'na sa senyeha nakong ea lipalangoang, e leng se hlahisang metsoako ea tlhaho e khomarelang molala kapa koana ea sefate. tlosa sekhahla ka har'a liphutheloana tsa eona 'me ka bonolo u sisinyehe ho tlohela lik'hemik'hale li oela tlaase ho sekoahelo. bakeng sa lihlahisoa tsa metsi, centrifuge ho 200-500 RPM ho bokella metsi ka tlaase ho sefate. leka ho qoba tahlehelo kapa ts'oaetso nakong ea ho sebetsana.

Litaelo tse ling

In Vitro le In Vivo Sebopeho sa Alkaloid Nuciferine phofo

(1) Tlhaloso
Lotus e halalelang (Nelumbo nucifera) e na le likokoana-hloko tse ngata tsa phyto le e nang le histori ea tšebeliso ea batho. E le hore re tsebe hore na lihlopha life li ka ba le boikarabello bakeng sa liphello tse tlalehiloeng tsa psychotropic, re ne re sebelisa lipolelo tsa silico tsa li-phytochemicals tse tsebahalang. Nuciferine phofo e tala, karolo ea alkaloid ea Nelumbo nucifera le Nymphaea caerulea, e ne e na le boprofeta ba limolek'hule tse tšoanang le li-antipsychotic compounds. Thuto ea rona e tsebahala ka Nuciferine phofo e sebelisoang ka in vitro le ka vivo ea litlhare tsa lithethefatsi.

(2) Mekhoa
Nuciferine phofo e tala e ne e khetholloa pele ka silico e sebelisa mokhoa oa ho tšoana, 'me e lateloa ke litlhaloso tse eketsehileng le ho netefatsoa ho sebelisa Psychoactive Drug Screening Program ea National Institute of Mental Health. Nuciferine phofo e ile ea lekoa ka nako e le 'ngoe ka karabo e ka sehloohong, tšebetso ea pele ho mokokotlo, ts'ebetso ea li-hyperlocomotor, le khethollo ea lithethefatsi.

(3) Sephetho
Nuciferine phofo e arolelana lefahleho la mokelikeli o tšoanang le li-antipyzotic like antipyzole drugs. Nuciferine phofo e tala e ne e le khahlanong le 5-HT2A, 5-HT2C, le 5-HT2B, e leng agonist e fapaneng ea 5-HT7, e leng agonist ea karoloana ho D2, D5 le 5-HT6, e leng agonist ea 5-HT1A le D4 receptors, 'me a thibela motlakase oa dopamine. Ka mefuta ea rodent e amanang le ts'ebetso ea lithethefatsi ea antipsychotic, phofo ea Nuciferine e thibiloe likarabo tsa hlooho le likotsi tsa khethollo tsa khethollo ea 5-HT2A, e nkeloa sebaka ke ho etsa khethollo ea khethollo ea clozapine, ts'ebetso ea amphetamine e ntlafalitsoeng, e thibelang mosebetsi oa ho lokisa li-phencyclidine (PCP) e pholositse pherekano e bakoang ke PCP ea ho thibela ho thibela tšoaetso ntle le ho kenngoa ha catalepsy.

(4) Liphello
Tlhaloso ea limolek'hule tsa phofo e tala ea Nuciferine e ne e le joalo empa ha e tšoane le eo e neng e arolelana le lithethefatsi tse ngata tse amohelehang khahlanong le likokoana-hloko tse bontšang hore phofo ea Nuciferine e na le liketso tse kang tsa antipychotic.

Nkhiferine Raw Powder (CAS 475-83-2)

Ntho e nyenyane 10grams.
Tlhahlobo ka bongata bo tloaelehileng (ka hare ho 1kg) e ka romeloa lihora tse 12 kamora ho lefa.
Bakeng sa tlhahiso e kholo (ka hare ho 1kg) e ka romeloa ka matsatsi a sebetsang a 3 ka mor'a ts'ebetso.

Khoebo ea Raw ea Nuciferine ea Rafi

Ho fanoa nakong e tlang.


Tsela ea ho reka phofo ea Nuciferine (CAS 475-83-2) ho tloha ho bahlahisi ba AASraw

1.To iteanye le rona ka imeile ea rona lenaneo la lipatlisiso, kapa skype ea inthanetengmoemeli oa tšebeletso ea bareki (CSR).
2.To re fane ka lipotso tsa hau le lipotso tsa hau.
3.Our CSR e tla u fa tlhaloso, nako ea ho lefa, nomoro ea ho latela, litsela tsa ho pepa le letsatsi la ho fihla ho fihlela (ETA).
4.Payment e entsoe mme thepa e tla romelloa ka lihora tsa 12 (Ho laela ka hare ho 10kg).
5.Goods e amohetse mme e fana ka litlhaloso.

TLHOKOMELISO LE TLHALOSO:

Boitsebiso bona bo rekisetsoe tšebeliso ea lipatlisiso. Lipehelo tsa thekiso Etsa kopo. Eseng molemong oa tšebeliso ea batho, kapa bongaka, bongaka ba liphoofolo kapa lisebelisoa tsa lapeng.


COA

COA 475-83-2 phofo ea Nuciferine AASRAW

HNMR

Phofo e meholo ea Nuciferine (475-83-2) hplc≥98% | Basebetsi ba AASraw

Recipes

Li-Recipe tsa Nuciferine Raw Recipes:

Ho botsa bareki ba rona baemeli ba rona (CSR) bakeng sa lintlha tse eketsehileng, bakeng sa boitsebiso ba hau.

Litlhaloso le lihlahisoa tsa lihlahisoa