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2-Methoxyestradiol (362-07-2)

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SKU: 362-07-2. Category:

AASraw e na le tšebeliso le bokhoni ba tlhahiso ho tloha gram ho isa ho boima ba 2-Methoxyestradiol (362-07-2), tlasa melaoana ea CGMP ea tsamaiso le tsamaiso ea boleng ba boleng.

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2-Methoxyestradiol (362-07-2) video


2-Methoxyestradiol (362-07-2) Specification:

Khemikhale ea Lik'hemik'hale: Name Product: 2-Methoxyestradiol
Reka 2-Methoxyestradiol (362-07-2) hplc≥98% | AASraw Cas.: 362-07-2
Molecular Formula: C19H26O3
Boima ba 'mele: 302.4
Li-synonyms: 2-Methoxyestradiol

362-07-2

Panzem

2-Methoxyestradiol-17beta

2-Hydroxyestradol 2-methyl ether

Sesebelisoa: E omileng, e lefifi
Litokomane (COA & HPLC jj.): fumaneha

2-Methoxyestradiol (362-07-2) Dtlhahlobo:

methoxyestradiol phofo, eo hape e tsejoang e le 2-ME, ke estradiol metabolite ka molomo e nang le ts'ebetso ea antineoplastic, ka hona ke angiogeneis inhibitorLe eona e sebetsa e le vasodilator.

2-Methoxyestradiol e thibela angiogeneis ka ho fokotsa ho eketseha ha sele le ho tsitsisa endophelial cell apoptosis. Moemeli enoa o boetse o thibela kholo ea lisele tsa tumor ka ho tlama ho tubulin, ho baka ts'ebetso ea antimitotic, le ho kenya ts'ebetso ea caspase, e lebisang ho ts'oaroa ha potoloho ea sele ka mokhatlong oa G2, ho phatloha ha DNA le apoptosis.

Tlhaloso:

  • 1: Perez-Sepulveda A, Espaà ± a-Perrot PP, Norwitz ER, Illanes SE. Litsela tsa Metabolic tse kenyang karolo ea 2-methoxyestradiol le karolo ea bona ho preeclampsia. Reprod Sci. 2013 Sep; 20 (9): 1020-9. doi: 10.1177 / 1933719113477483. Epub 2013 Mar 1. Tlhahlobo. PubMed PMID: 23456663; PubMed Central PMCID: PMC3745713.
  • 2: Machado-Linde F, Pelegrin P, Sanchez-Ferrer ML, Leon J, Cascales P, Parrilla JJ. 2-methoxyestradiol ho pathophysiology ea endometriosis: tsepamisa maikutlo ho angiogeneis le hobeng monyetla oa phekolo. Reprod Sci. 2012 Oct; 19 (10): 1018-29. doi: 10.1177 / 1933719112446080. Epub 2012 Aug 8. Tlhahlobo. PubMed PMID: 22875846.
  • 3: Peyrat JF, Brion JD, Alami M. Synthetic 2-methoxyestradiol derivatives: likamano tsa tšebetso-karolo. Curr Khem Chem. 2012; 19 (24): 4142-56. Tlhahlobo. PubMed PMID: 22709003.
  • 4: Verenich S, Gerk PM. Litšepiso tsa kalafo ea 2-methoxyestradiol le liphephetso tsa eona tsa tšebeliso ea lithethefatsi. Mol Mof. 2010 Dec 6; 7 (6): 2030-9. Doi: 10.1021 / mp100190f. Epub 2010 Oct 21. Tlhahlobo. PubMed PMID: 20831190; PubMed Central PMCID: PMC3059899.
  • 5: Mueck AO, Seeger H. 2-Methoxyestradiol-biology le mokhoa oa ts'ebetso. Li -teroids. 2010 Oct; 75 (10): 625-31. Doi: 10.1016 / j.steroids.2010.02.016. Epub 2010 Mar 7. Tlhahlobo. PubMed PMID: 20214913.

TLHOKOMELISO LE TLHALOSO:

Boitsebiso bona bo rekisetsoe tšebeliso ea lipatlisiso. Lipehelo tsa thekiso Etsa kopo. Eseng molemong oa tšebeliso ea batho, kapa bongaka, bongaka ba liphoofolo kapa lisebelisoa tsa lapeng.


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