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Pente ea Eplerenone (107724-20-9)

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AASraw e na le bokhoni ba tlhahiso le tlhahiso ho tloha ho gram ho ea ka taelo e kholo ea phofo ea Eplerenone (107724-20-9), tlas'a taolo ea CGMP le tsamaiso ea tšebetso ea boleng bo sebetsang.

Eplerenone phofo ke mohanyetsi oa li-aldosterone haholoanyane bakeng sa mokelikeli oa mineralocorticoid ho feta spironolactone, o nang le kamano e tlaase ea progesterone, androgen, le recepors ea glucocorticoid. Bakeng sa ntlafatso ea ho phela ha bakuli ba tsitsitseng ba nang le li-systolic ho se sebetse (karoloana ea ejection <40%) le bopaki ba tlhokomelo ea pelo ea congestive heart failure ka mor'a lefuba le matla la ho fokotsa likokoana-hloko.

Tlhaloso ea Sehlahisoa

Video ea eplerenone ea phofo


Eplerenone phofo ea basebetsi ba motheo

Name: Eplerenone phofo
CAS: 107724-20-9
Ho hloeka: 99% min (HPLC)
Molecular Formula: C24H30O6
Boima ba 'mele: 414.49
EINECS: 1308068-626-2
Li-synonyms: pregn-4-sep-7,21-dicarboxylic acid e 9,11-epoxy-17-hydroxy-3-oxo sa gamma-lactone methylene Ester; EPLERENONE 98%; EPLERENONE USP Standard; Elperenone; EplerenoneC24H3006; acid e pregn-4-sep-7,21-dicarboxylic, 9,11-epoxy-17-hydroxy-3-oxo, γ-lactone, methyl ester (7 α, 11 α, 17 α;) EPLERENONE LE N-1 SEBELENG; epoxymexrenone
Melt Point: 241-243 ° C
Alpha: D + 5 ° (c = 0.437 ka chloroform)
Temp Temp Storage: Boloka ho RT
Solubility DMSO: ho qhibiliha2mg / mL, ho hlakile (ho futhumala)
Color: Ho soeufetse ho fihlela ho e-na le phofo e tšoeu ea kristale


Seo U Batlang ho se Tseba ka Peso ea Eplerenone

lebitso

Pente ea Eplerenone (AASraw)

Se phofo ea Eplerenone ke eng

Phofo ea Eplerenone ke mohanyetsi oa molomo oa aldosterone o kang molomo oa spironolactone, o ka sebelisoang o le mong kapa o kopantsoe le meriana e meng ho phekola khatello e matla ea mali. E sebetsa ka ho thibela lik'hemik'hale (aldosterone) 'meleng oa hau o fokotsang palo ea sodium le metsi eo' mele o e bolokang. Ho fokotsa khatello ea mali e phahameng ho thusa ho thibela lipolao, tlhaselo ea pelo le mathata a liphio. E boetse e sebelisetsoa ho sebetsana le ho hlōleha ha pelo ea pelo ho latela lefu la pelo. Ntle ho moo, phofo ea Eplerenone e ntse e hlahlojoa e le phekolo ea bo-retinopathy ba bohareng ba serous.

Joang phofo ea Eplerenone e nkiloe hantle joang

U sebelisa phofo ea Eplerenone joalokaha ngaka ea hao e laetse, hangata hanngoe kapa habeli ka letsatsi. Latela litaelo tsa lebokose la lengolo la ngaka, sebelisa meriana ena khafetsa e le hore u fumane molemo o moholo ho eona. Hopola ho e sebelisa ka nako e le 'ngoe letsatsi le leng le le leng. Litekanyetso li thehiloe boemong ba hau ba bongaka (khatello e phahameng ea mali, pelo e senyehileng), karabelo ea phekolo, le meriana e meng eo u ka e nkang. Ba bonnete ba hore bolella ngaka ea hao 'me pharmacist ka lihlahisoa tsohle tseo u li sebelisa (ho akarelletsa le lithethefatsi lengolo la ngaka, nonprescription lithethefatsi,' me lihlahisoa tsa litlama) ngaka .Your ka 'na ka linako tse ling fetola lethal dose ya hao ho etsa bonnete ba hore u fumana molemo ka ho fetisisa results.Eplerenone phofo e ka etswa ka kapa ntle le lijo.Ko etsa bonnete ba hore meriana ena e thusa boemo ba hau ebile ha e bake liphello tse kotsi, khatello ea mali ea hau e tla lokela ho hlahlojoa hangata. Maemong a hau a potassium a tla hloka ho hlahlojoa le liteko tsa khafetsa tsa mali. Etela ngaka ea hau kamehla.

Haeba u ntse u phekoloa bakeng sa khatello e matla ea mali, u 'ne u sebelise meriana ena esita leha u ikutloa u phela hantle. Hangata khatello ea mali e phahameng ha e na matšoao. U ka 'na ua hloka ho sebelisa meriana ea khatello ea mali bophelo bohle ba hao.

Boloka mocheso oa motšehare ho tloha mongobo le mocheso.

Temoso ho Eplerenone phofo

Phofo ea Eplerenone e lokela ho sebelisoa ka hloko ka:

bakuli ba tšoeroeng ke liphio kapa sebete, ba nkang lithium (ka tloaelo ba fanoang bakeng sa lefu la ho ferekana kelellong), le ba nkang tacrolimus kapa ciclosporin (e sebelisetsoang ho thibela manyolo ka mor'a ho kenya kapa ho tšoara maemo a letlalo joalo.
E se ke ea sebelisoa ho:

bakuli ba nang le allergic (hypersensitive) ho eplerenone phofo kapa lits'ebetsong leha e le life tsa meriana (e kang lactose), bakuli ba nang le potassium e phahameng maling (hyperkalaemia), ba nang le lefu la liphio tse lekaneng le le matla, ba nang le sebete se matla maloetse, bana, bakuli ba noang meriana bakeng sa tšoaetso ea fungal (ketoconazole kapa itraconazole), meriana e thibelang likokoana-hloko bakeng sa HIV (nelfinavir kapa ritonavir), lithibela-mafu (clarithromycin kapa telithromycin), nefazodone bakeng sa ho tepella maikutlo, kapa lithethefatsi ho thusa 'mele hore o hloke metsi a mangata a kang potassium diuretics le 'lipilisi tsa letsoai' (potassium supplements).

Pele u nka phofo ea Eplerenone, e-re ngaka ea hao e tsebe hore na u na le, kapa u kileng ua ba le eona:
lefu la tsoekere

  • Etsa mosebetsi o bobe oa liphio (lefu la liphio)
  • Likokoana-hloko ho meriana leha e le efe
  • Potassium e phahameng maemong a hao a mali (hyperkalemia)
  • lefu le matla la liphio (lefu la sebete)
  • Li-cholesterol tse phahameng kapa maemo a triglyceride
  • Gout (e leng mofuta oa ramatiki o bakoang ke khalase ea uric acid ka manonyeletso)

Bakuli ba nang le allergic (hypersensitive) ho Eplerenone powder kapa ho tse ling tse ling tsa meriana (e kang lactose), bakuli ba nang le potassium e phahameng maling (hyperkalaemia), ba nang le lefu la liphio tse boima ho isa boima, ba nang le sebete se matla maloetse, bana, bakuli ba noang meriana bakeng sa tšoaetso ea fungal (ketoconazole kapa itraconazole), meriana e thibelang likokoana-hloko bakeng sa HIV (nelfinavir kapa ritonavir), lithibela-mafu (clarithromycin kapa telithromycin), nefazodone bakeng sa ho tepella maikutlo, kapa lithethefatsi ho thusa 'mele hore o hloke metsi a mangata a kang potassium diuretics le 'lipilisi tsa letsoai' (potassium e tlatsitseng)

Ngaka ea hau e ka 'na ea khothaletsa hore u je lijo tse nang le letsoai le tlaase nakong ea phekolo ea hau le phofo ea Eplerenone. Latela litaelo tsena ka hloko. Bolella ngaka ea hau hore u noa meriana ena pele u e-na le mofuta ofe kapa ofe oa bongaka kapa oa meno. Boloka likhetho tsohle le ngaka ea hau le laboratori ha u ntse u sebelisa Eplerenone phofo. Mofani oa hao oa tlhokomelo ea bophelo o tla batla ho etsa liteko tse tloaelehileng ho hlahloba karabo ea 'mele oa hau ho lithethefatsi ena. Lithethefatsi tse ling ha lia lokela ho sebelisoa hammoho le phofo ea Eplerenone. Bolella ngaka ea hau haeba u nka e 'ngoe ea tse latelang:

  • Midamor (amiloride)
  • Dyrenium (triamterene)
  • Nizoral (ketoconazole)
  • Boimana le phofo ea Eplerenone
  • Aldactone (spironolactone)
  • Amiloride le hydrochlorothiazide
  • Spelanox kapa Onmel (itraconazole)
  • Aldactazide (spironolactone le hydrochlorothiazide)
  • Dyazide kapa Maxzide (triamterene le hydrochlorothiazide)
  • Potassium e tlatsetsang, kapa libaka tse kenang letsoai tse nang le potassium

Pele o qala ka phofo ea Eplerenone, bolella ngaka ea hao haeba u imme, kapa u rerile ho ima. U tla lokela ho buisana ka melemo le likotsi tsa ho noa meriana nakong ea bokhachane. Ha ho sa tsejoe hore na Eplerenone phofo e feta lebese la lebese. U se ke ua anyesa lesea ha u ntse u sebelisa meriana ena.

Eplerenone phofo

Ntho e nyenyane 10grams.
Tlhahlobo ka bongata bo tloaelehileng (ka hare ho 1kg) e ka romeloa lihora tse 12 kamora ho lefa.
Bakeng sa tlhahiso e kholo (ka hare ho 1kg) e ka romeloa ka matsatsi a sebetsang a 3 ka mor'a ts'ebetso.

Eplerenone phofo Khoebo

Ho fanoa nakong e tlang.


Ho reka phofo ea Eplerenone ho tloha ho AASraw

1.To iteanye le rona ka imeile ea rona lenaneo la lipatlisiso, kapa skype ea inthanetengmoemeli oa tšebeletso ea bareki (CSR).
2.To re fane ka lipotso tsa hau le lipotso tsa hau.
3.Our CSR e tla u fa tlhaloso, nako ea ho lefa, nomoro ea ho latela, litsela tsa ho pepa le letsatsi la ho fihla ho fihlela (ETA).
4.Payment e entsoe mme thepa e tla romelloa ka lihora tsa 12 (Ho laela ka hare ho 10kg).
5.Goods e amohetse mme e fana ka litlhaloso.

TLHOKOMELISO LE TLHALOSO:

Boitsebiso bona bo rekisetsoe tšebeliso ea lipatlisiso. Lipehelo tsa thekiso Etsa kopo. Eseng molemong oa tšebeliso ea batho, kapa bongaka, bongaka ba liphoofolo kapa lisebelisoa tsa lapeng.


COA

COA 107724-20-9 Eplerenone phofo AASRAW

HNMR

107724-20-9 Eplerenone AASRAW HNMR

Recipes

Eplerenone phofo Recipes

Ho botsa bareki ba rona baemeli ba rona (CSR) bakeng sa lintlha tse eketsehileng, bakeng sa boitsebiso ba hau.

Litlhaloso le lihlahisoa tsa lihlahisoa