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Apatinib (811803-05-1)

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AASraw e na le bokhoni ba tlhahiso le tlhahiso ho tloha ho gram ho ea ka taelo ea Apatinib (CAS 811803-05-1), tlas'a taolo ea CGMP le tsamaiso ea mokhoa oa ho laola boleng.

Apatinib, molek'hule e nyane ea tyrosine kinase inhibitor e thibelang vascular endothelial kholo factor receptor-2, e amoheletsoe bakeng sa metastatic adenocarcinoma Chaena ka Oct 2014. Ena ke tlaleho ea pele mabapi le tšebeliso ea eona bakeng sa kankere e tsoetseng pele ea lefuba e le mofuta oa phekolo ea moriana oa boraro ho fihlela joale.

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Apatinib Matšoao a motheo

Name: Apatinib
CAS: 811803-05-1
Molecular Formula: C24H23N5O
Boima ba 'mele: 397.47232
Melt Point: 111-114 ° C
Temp Temp Storage: -20 ° C
Color: Lebala le Lefubelu le Lebala le Tiileng


Apatinib (811803-05-1) tshebeliso ea potoloho ea steroids

Mabitso

Apatinib (CAS 811803-05-1), e tsejoang hape e le YN968D1, Mesylate.

Sebeliso ea Apatinib

Bakuli ba kankere ba ne ba fokotsoa ka mefuta e fapaneng ea Apatinib letsatsi le leng le le leng bakeng sa matsatsi a 28. Apatinib e ne e mamelloa hantle ka tekanyo e ka tlaase ho 750 mg / letsatsi, 3 ea 3 tekanyetso ea menyetla e fokolang e ileng ea tlalehoa ho 1000 mg / letsatsi le tekanyo e phahameng e mamelletsoeng e khetholloa ho be850 mg / letsatsi.

Temoso ho Apatinib

U tlameha ho tseba litla-morao ha u nka Apatinib. Litla-morao tse tloaelehileng tsa apatinib e ne e le khatello ea kelello le lefu la matsoho; Leha ho le joalo, toxicity ea apatinib e ne e laoloa ebile e mamelleha.

Litaelo tse ling

Rivoceranib (Apatinib, YN968D1) ke mokhethoa oa lithethefatsi oa lithethefatsi o sebelisoang ka molomo o hlahisoang ka ntle ho Chaena ka LSK BioPharma, bakeng sa phekolo ea lithethefatsi tse matla tse kang kankere e tsoetseng pele kapa metastatic gastric, lefu la colorectal le hepatocellular carcinoma. YN968D1 e ne e qalisoa pele e bile e na le patente ea Advenchen Laboratories e Southern Southern California. Kajeno Apatinib e rekisoa Chaena bakeng sa kankere e tsoetseng pele ea gastric ke mo-Chinese-territory license holder-holder, Jiangsu Hengrui MedicineCo., Ltd tlasa lebitso la Aitan®. LSK BioPharma e na le litokelo tsa lefats'e (ntle le Chaena) mme li kopantsoe le nts'etsopele le papatso ea rivoceranibin South Korea.

Rivoceranib ke khetho e kholo ea matla a sefate a ho qetela a matla a ho hōla-2 (e tsejoang e le VEGFR2) e tsamaisang tsela e ka sehloohong bakeng sa tumor-mediatedangiogenesis. E 'nile ea lekoa ka bongaka ho bakuli ba 1,000 lefatšeng lohle' me ea sebetsa ka matla ho kankere e mengata ho akarelletsa le kankere ea gastric, kankere e bolaeang, hepatocellular carcinoma, kankere e seng e nyenyane ea kankere ea matšoafo, kankere ea esophageal, thyroidcancer, mesothelioma le li-tumorous neuroendocrine. E boetse e bontšitse bokhoni ba ho ntlafatsa liphello tse kopaneng le chemotherapeutics le immunotherapy, hammoho le phekolo ea tlhokomelo.


Joang ho reka Apatinib ho AASraw

1.To iteanye le rona ka imeile ea rona lenaneo la lipatlisiso, kapa skype ea inthanetengmoemeli oa tšebeletso ea bareki (CSR).
2.To re fane ka lipotso tsa hau le lipotso tsa hau.
3.Our CSR e tla u fa tlhaloso, nako ea ho lefa, nomoro ea ho latela, litsela tsa ho pepa le letsatsi la ho fihla ho fihlela (ETA).
4.Payment e entsoe mme thepa e tla romelloa ka lihora tsa 12 (Ho laela ka hare ho 10kg).
5.Goods e amohetse mme e fana ka litlhaloso.

TLHOKOMELISO LE TLHALOSO:

Boitsebiso bona bo rekisetsoe tšebeliso ea lipatlisiso. Lipehelo tsa thekiso Etsa kopo. Eseng molemong oa tšebeliso ea batho, kapa bongaka, bongaka ba liphoofolo kapa lisebelisoa tsa lapeng.


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