USA Tsamaiso ea malapeng, Canada Tlhabollo ea malapeng, Tlhabollo ea malapeng ea Europe

Trilostane Powder (13647-35-3)

Rating: SKU: 13647-35-3. Category:

AASraw e na le tšebeliso le bokhoni ba tlhahiso ho tloha ho gram ho isa ho boima ba Trilostane Powder (13647-35-3), tlasa taolo ea CGMP le tsamaiso ea boleng ba taolo ea boleng.

Tlhaloso ea Sehlahisoa

Trilostane Powder (13647-35-3) video


Trilostane Powder (13647-35-3) Specification:

Khemikhale ea Lik'hemik'hale: Name Product: Trilostane
Cas.: 13647-35-3
Molecular Formula: C20H27NO3
Boima ba 'mele: 329.43
tekanyetso ena: Ka tlung
Sesebelisoa: E omileng, e lefifi le ka 0 - 4 C ka nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C ka nako e telele (likhoeli ho isa ho lilemo).
Litokomane (COA & HPLC jj.): fumaneha

Trilostane Powder (13647-35-3) Dtlhahlobo:

Trilostane phofo ke inhibitor ea 3β-hydroxysteroid dehydrogenase e sebelisoang kalafo ea Cushing's syndrome le hyperaldosteronism ea mantlha. Tsena ke litšitiso tseo ka tsona ho hlahisoang lihormone tse ngata tsa 'mele' meleng. Corticosteroids e bohlokoa bakeng sa 'mele ho sebelisa lik'habohaedreite, mafura le liprotheine le karabelo e tloaelehileng ho khatello ea maikutlo. Li boetse li hlokahala bakeng sa taolo ea letsoai le tekanyo ea metsi 'meleng. Trilostane phofo e thusa ho thibela tlhahiso ea corticosteroids, ho laola matšoao a amanang le mafu ana.

Trilostane phofo le eona e ka ba molemo ho kalafo ea mofetše oa matsoele e khutletseng ho basali ba fetileng ho khaotsa ho ilela khoeli.

E sa tsoa amoheloa ka selemo sa 2008 bakeng sa kalafo ea lefu la Cushing (hyperandrenocorticism) ho lintja. Hape ke sethethefatsi sa pele se amohetsoeng ho alafa Cushing le likolong tsa lintja. Moriana ona o tlamang o sebetsa ka ho emisa tlhahiso ea cortisol litšoeleng tsa adrenal.

Tlhaloso:

  • 1: Midence JN, Drobatz KJ, Hess RS. Cortisol Concentrations ho Ntja tse laoloang Hantle ka Hyperadrenocorticism E Ts'oeroe ka Trilostane. J Vet Intern Med. 2015 Nov; 29 (6): 1529-33. doi: 10.1111 / jvim.13615. Epub 2015 Sep 16. PubMed PMID: 26374943.
  • 2: Fracassi F, Corradini S, Floriano D, Boari A, Aste G, Pietra M, Bergamini PF, Dondi F. Practostic lintlha tsa ho pholoha ho lintja tse nang le hypercortisolism e itšetlehileng ka pituitary tse tšoaroang ka trilostane. Vet Rec. 2015 Jan 10; 176 (2): 49. Doi: 10.1136 / vr.102546. Epub 2014 Aug 28. PubMed PMID: 25170036.
  • 3: Bonadio CM, Feldman EC, Cohen TA, Kass PH. Papiso ea litekanyetso tsa li-hormone tsa adrenocorticotropic li qalile 2 bapisoa le lihora tse 4 kamora ho tsamaisoa ha trilostane ho lintja tse nang le tlhaho ea hyperadrenocorticism. J Vet Intern Med. 2014 Jul-Aug; 28 (4): 1239-43. doi: 10.1111 / jvim.12357. Epub 2014 Mots'eanong 26. PubMed PMID: 24863172.

TLHOKOMELISO LE TLHALOSO:

Boitsebiso bona bo rekisetsoe tšebeliso ea lipatlisiso. Lipehelo tsa thekiso Etsa kopo. Eseng molemong oa tšebeliso ea batho, kapa bongaka, bongaka ba liphoofolo kapa lisebelisoa tsa lapeng.


COA

HNMR

Litlhaloso le lihlahisoa tsa lihlahisoa